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Jianzhong Su, Ph.D.
Professor
Principal Investigator
sujz@wibe.ac.cn

Jianzhong Su received a PhD in Mathematics from Harbin Institute of Technology in 2013. In 2014, he joined Wei Li's lab, Division of Biostatistics, Baylor College of Medicine as a postdoctoral fellow. Major in epigenetic alteration in disease development based on big data analysis of next-generation sequencing data. He is a Professor with the College of Biomedical engineering in Wenzhou Medical University and Wenzhou Institute of Biomaterials & Engnineering, CAS. His research focuses on precise identification of epigenetically-regulated cancer driver targets for cancer diagnosis and therapeutic intervention by incorporating computational predication and genome-wide CRISPR screening validation, bioinformatics platform development for high-throughput sequencing data and single-cell DNA methylation, and Evolution and allelic architecture of complex disease.


Faculty


Meng Zhou, PhD
Associate Professor
biofomeng@hotmail.com

Meng Zhou received a PhD in Bioinformatics from Jilin University in 2016. His research focuses on computational identification and characterization of disease-associated ncRNAs (miRNA, lncRNA and circRNA) based on transcriptome profiling (Microarray and RNA-Seq), and development of computational methods and database for functional interpretations of ncRNAs and disease.

Jie Sun, PhD
Associate Professor
suncarajie@hotmail.com

Jie Sun received a PhD in Bioinformatics from Harbin Medical University in 2012. Her research focuses on Molecular biomarkers detection in cancer diagnosis, prognosis and chemotherapy resistance based on multi-omics cancers data, and development of Artificial Intelligence algorithm in medical diagnosis and treatment.

Yan Zhang, Ph.D.
Research Assistant
zyan0626@163.com

Yan Zhang received a PhD in Bioinformatics from Harbin medical university in 2018. Her research focuses on Cancer Systems Biology: Identification the biomarkers for diagnosis and prognosis of cancer and exploration how perturbations of biological networks lead to cancer, and computational pharmacogenomics: Prediction individual drug responses and new drug combinations for treatment of chemoresistant patients, contributing to realize precision medicine.

Fulong Yu, PhD
Research Assistant
yufulong421@gmail.com

Fulong Yu received a PhD in Bioinformatics from Harbin medical university in 2018. His research focuses on developing computational algorithms and statistical methods to solve problems that stem from large-scale biological data generated by high-throughput sequencing technologies.

Jian Yuan, PhD
Research Assistant
yuanjian0415@gmail.com

Jian Yuan received a MS in Evolutionary biology from Anhui Normal University in 2014. His research focuses on evolution and allelic architecture of complex disease: investigate the impact of common and rare genetic variants to both the non-Mendelian and Mendelian phenotype, and genetic and epigenetic mechanism of Cancer occurrence and Metastasis.

Xinyu Wang, PhD
Research Assistant
wangxinyuhs@126.com

Xinyu Wang received a MS in Bioinformatics from Harbin Medical University in 2017. His research focuses on Computational Epigenetics and NGS.

Kai Li, PhD
Research Assistant
LeeKacle@126.com

Kai Li received a MS in Biomedical Engineering from South-Central University For Nationalities in 2017. His research focuses on Development of statistical methods and algorithms for single-cell DNA methylation and RNAseq.


Students


Zhengbo Xue
Graduate Student


Dandan Fan
Graduate Student

Qi Jiang
Graduate Student

Siqi Bao
Graduate Student

Yaru Zhang
Graduate Student

Ping Hou
Graduate Student

Xinghui Li
Undergraduate Student

Qian Wu
Undergraduate Student

Jingjing Fang
Undergraduate Student


Collaborators


Dr. Wei Li, Baylor College of Medicine, USA

Dr. Margaret Goodell, Baylor College of Medicine, USA

Dr. Kaifu Chen, Cornell University, USA

Dr. Yingli Sun, Beijing Institute of Genomics, CAS, China

Dr. Xiaotian Zhang, Van Andel Research Institute, USA

Dr. Yingzi Yang, Harvard School of Dental Medicine, USA

Dr. Nan Wu, Peking Union Medical College Hospital, China

Dr. Jiangfan Chen, Wenzhou Medical University, China

Dr. Zibing Jin, Wenzhou Medical University, China

Dr. Hao Chen, Wenzhou Medical University, China

Dr. Jinyi Zhang, Wenzhou Medical University, China

Dr. Xiangtian Zhou, Wenzhou Medical University, China

Dr. Shen Li, Zhejiang University, China

Dr. Yan Zhang, Harbin Institute of Technology, China
Dr. Yan Zhou, Shenzhen University, China

 

Lab Alumni


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