张琪
助理研究员
本科毕业于哈尔滨医科大学，博士毕业于中国科学院大学北京基因组研究所（国家生物信息中心）。
邮箱：zhangqi@wmu.edu.cn
研究方向
- 结合人工智能、生物信息学和单细胞多组学测序等，探究视网膜发育、再生过程及衰老相关疾病的核心分子机制，为疾病干预提供理论支撑。
- 单细胞多组学算法开发、优化及应用研究。
代表性论文
- Qi Zhang, Yezhen Tan, Qiyang Liang, Liangyou Gu, Yue Shi, Yan Huang, Xiubin Li, Jie Qi, Cheng Peng, Hanfeng Wang, Kan Liu, Tianwei Cai, Yaohui Wang, Yudan He, Qingbo Huang, Xu Zhang, Baojun Wang, Xin Ma, and Weimin Ci. The extracellular-matrix-remodeling capability exposes therapeutic vulnerability in a subset of renal cell carcinomas with tumor thrombi. Dev Cell. 2025 Dec 1;60(23):3201-3221.e15. (Featured Article; Preview by Dev Cell, 2025 Dec 1;60(23):3153-3155)
- Yue Shi, Qi Zhang, Hai Bi, Min Lu, Yezhen Tan, Daojia Zou, Liyuan Ge, Zhigang Chen, Cheng Liu, Weimin Ci, Lulin Ma. Decoding the multicellular ecosystem of vena caval tumor thrombus in clear cell renal cell carcinoma by single-cell RNA sequencing. Genome Biol. 2022 Mar 31;23(1):87.
- Jianye Zhang, Qi Zhang, Gang Lin, Ying Wang, Juan Li, Ping Wang, Jie Qi, Yuan Liang, Shanyuan Chou, Shiming He, Yanqing Gong, Ninghan Feng, Yang Wang, Yuanyuan Ma, Mei Zhang, Yue Shi, Xuesong Li, Weimin Ci, Liqun Zhou. Single-Cell Analysis Reveals that Vitamin C Inhibits Bone Metastasis of Renal Cancer via Cell Cycle Arrest and Microenvironment Remodeling. Adv Sci (Weinh). 2025 Aug;12(30):e01011.
- Shiyuan Wang, Qi Zhang, Chunlu Yu, Yiyin Cao, Yongchun Zuo, Lei Yang. Immune cell infiltration-based signature for prognosis and immunogenomic analysis in breast cancer. Brief Bioinform. 2021 Mar 22;22(2):2020-2031.
- Qi Zhang, Yezhen Tan, Jianye Zhang, Yue Shi, Jie Qi, Daojia Zou, Weimin Ci. Pyroptosis-Related Signature Predicts Prognosis and Immunotherapy Efficacy in Muscle-Invasive Bladder Cancer. Front Immunol. 2022 Apr 11:13:782982