计算生物学与转化医学实验室(Su Lab)

Computational Tools

Algorithm

QDMR

QDMR (Quantitative Differentially Methylated Regions) is a quantitative approach to quantify methylation difference and identify DMRs from genome-wide methylation profiles by adapting Shannon entropy.

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Web Platform

scTPA

A web-based platform providing functional interpretation and annotation for scRNA-seq data using pathways activation signatures in human and mouse.

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Prediction Model

DrABC

A phenotype-based GPV risk prediction model of DNA-repair Associated Breast Cancer (DrABC).

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Method

scPagwas

A polygenic principal component-scoring method that links scRNA-seq data with large-scale GWAS summary statistics to prioritize genetics-modulated cells associated with complex diseases.

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Databases

Database

SEA

Super-Enhancer Archive is a web based comprehensive resource focuses on the collection, storage and online analysis of super-enhancers.

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Atlas

CFEA

A cell-free epigenome atlas in human diseases.

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Knowledgebase

Nc2Eye

A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

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Database

EyeDiseases

A comprehensive database dedicated to genetics variants, gene expression and epigenetic factors in 73 kinds of human eyes diseases.

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Database

scHOB

scHOB is a comprehensive database consisting of all the scRNA-seq data on 10 kinds of human organoids with millions of cells, as well as a knowledgebase that assembles the experimental parameters of published organoid-related experiments was constructed for transparent reporting.

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